标题:Chiral 1H NMR of Atropisomeric Quinazolinones With Enantiopure Phosphoric Acids
Abstact:A chiral phosphoric acid promoted enantioselective NMR analysis of atropisomeric quinazolinones was described, in which a variety of racemic arylquinazolinones such as afloqualone and IC-87114 were well recognized with up to 0. 21 ppm 11δ value. With this method, the optical purities of different non-racemic substrates can be fast evaluated with high accuracy.
原文链接:
https://doi.org/10.3389/fchem.2018.00300